Mass General Brigham • 14th May 2025

Q&A: ‘Cell Line Atlas’ Provides a Crucial Resource for Developing Therapies for Biliary Tract Cancer

Nabeel El-Bardeesy, PhD, the John R. Gallagher III and Katherine A. Gallagher Endowed Chair in Gastrointestinal Cancer Research at Massachusetts General Hospital and an associate member at the Broad Institute, is a co-senior author of a paper published in Cancer Discovery.

Mass General Brigham • 24th April 2025

Q&A: IV Magnesium Reduces Kidney Damage from Cisplatin Chemotherapy

Shruti Gupta, MD, MPH, and David Leaf, MD, MMSc, of the Renal Division, Department of Medicine at Brigham and Women’s Hospital are the first and senior authors, respectively, of a paper published in JAMA Oncology, “Intravenous Magnesium and Cisplatin-Associated Acute Kidney Injury: A Multicenter Cohort Study.”

Massachusetts General Hospital • 24th March 2025

Q&A: Understanding the Role of Biological Sex in Age-Related Neurological Diseases

Anna K. Bonkhoff, MD and Natalia S. Rost, MD, MPH, of the Department of Neurology at Massachusetts General Hospital, are the lead and senior author, respectively, of a paper published in Science Advances titled “Sex differences in age-associated neurological diseases—A roadmap for reliable and high-yield research.”

Massachusetts General Hospital • 20th March 2025

Q&A: Simulation Model Shows Potential Affordability of Preventative HIV Therapy for Infants

Christopher Alba, of the Medical Practice Evaluation Center at Massachusetts General Hospital (MGH) is the lead author and Caitlin Dugdale, MD, MSc of the Division of Infectious Diseases at MGH, is the senior author of a paper published in PLOS One, Cost-effectiveness of broadly neutralizing antibodies for HIV prophylaxis for infants born in settings with high HIV burdens.

Mass General Brigham • 18th March 2025

A Peek Inside the Brain: Can You Guess What the Image Is?

The brain is home to many biological processes that keep us alive and help make us who we are. Zooming in to the details of the underlying biology of the brain not only reveals fascinating research stories — it also creates stunning works of art!
Check out these brain-related images from the annual Mass General Research Institute Image Awards that celebrate the beauty of research at Mass General Brigham and the incredible discoveries happening every day within the walls of our system.
Can you...

Massachusetts General Hospital • 10th March 2025

Q&A: Researchers Identify Link to Kidney in Myotonic Dystrophy Type 1

Thurman M. Wheeler, MD, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in Nature Communications, “Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1.”

Brigham Clinical & Research News • 4th March 2025

Q&A: Identifying Intimate Partner Violence with a Radiology Screening Tool

Patrick J. Lenehan, MD, PhD and Anji Tang, MD are co-first authors, and Bharti Khurana, MD, MBA, in the Department of Radiology Trauma Imaging Research and Innovation Center (TIRIC) at Brigham and Women’s Hospital, is the corresponding author of a paper published in the Journal of the American College of Radiology (JACR), “Utilizing Radiology as a Screening Tool to Identify Intimate Partner Violence.”

Intimate partner violence (IPV) is very common, with over 40% of women in the United States ex...

Mass General Brigham • 6th February 2025

Research Highlights for World Cancer Day: Finding Ways to Improve Outcomes and Reduce Cancer’s Burden | Mass General Brigham

Early detection and prevention remain key strategies to reduce the worldwide burden of cancer.
In recognition of World Cancer Day on Feb. 4th, here are some recent highlights from Mass General Brigham investigators who are spearheading research-driven advances in cancer treatment, prevention and detection.

Brigham Clinical & Research News • 3rd February 2025

Q&A: Predicting Consciousness After Cardiac Arrest with an EEG-based Model

Christopher Connor, MD, PhD, of the Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, is the senior author, and Samuel B. Snider, MD, of the Division of Neurocritical Care at Brigham and Women’s Hospital, is the first author of a paper published in Anesthesiology, “Developing an EEG-based model to predict awakening after cardiac arrest using partial processing with the BIS Engine.”

NeuWrite San Diego • 31st October 2024

The Double-Edged Sword of Cellular Senescence

Why do some cells age gracefully and others lead to disease? Cellular senescence is a hot topic in aging and disease research, but it is a bit of a double-edged sword. This fascinating process can be both a friend and a foe to our health, playing both beneficial and detrimental roles.

NeuWrite San Diego • 22nd August 2024

The Science of Sensitivity

I am driving home as the sun beams through the windshield and straight into my face. It’s beautiful: the orange glow of the golden hour sky, the demanding brightness seen through squinted eyes. But it also adds to my dread about the half-an-hour of incoming stop-and-go traff...

NeuWrite San Diego • 27th June 2024

Calico Cuties: Why These Colorful Cats Are (Almost) Always Female

Learn about the fascinating genetic reason for these felines' iconic orange, black, and white fur.

NeuWrite San Diego • 23rd May 2024

The Primordial Puzzle

The Debate Surrounding Life’s First Molecule

Few questions are more basic and more human than wondering how we came to exist. How did life arise from nonliving matter to produce the extraordinary diversity of nature: the colors in the flowers, the sophisticated ecosystems, the complexity of the brain, and its ability to hold our thoughts and feelings and enable us to ask these questions in the first place?